What is Abortion Pill Reversal Therapy?

Abortion Pill Reversal (APR) is a safe and effective therapy that reverses the abortive effect of mifepristone. APR gives women a chance to change their mind after taking the abortion pill. This therapy has reversed over 5000 abortions in 93 countries.

The abortion pill is a two-drug regimen: mifepristone followed by misoprostol 24-48 hours later

Progesterone is a natural hormone that plays a critical role in supporting a healthy pregnancy. It prepares the uterus for embryo implantation, promotes placental development, and suppresses uterine contractions., Mifepristone (Mifeprex) competitively inhibits the mother's progesterone, separating the embryo from the mother's uterus, and causing embryo death. Misoprostol (Cytotec) causes uterine contractions and expels the embryo.

Two-thirds (66%) of women can continue their pregnancies after Abortion Pill Reversal

APR therapy involves giving the mother progesterone by a capsule or injection after taking mifepristone. APR increases progesterone concentration levels to better compete with mifepristone and restore a normal pregnancy. Research shows that 66% of women who receive progesterone soon after starting the abortion pill can safely continue their pregnancies., , , , ,

Studies show that Abortion Pill Reversal is safe

Doctors have safely used progesterone during pregnancy for over 50 years., , , , Some medical organizations endorse APR as safe and effective. Other medical organizations oppose APR as unsafe and unproven. The only evidence cited by those who oppose APR is a small trial of 10 women. Five women received mifepristone plus placebo, and five received mifepristone plus APR. Study results showed that two of five women (40%) in the placebo group needed an emergency medical procedure, and one also required a blood transfusion. However, none of the women in the APR group required medical intervention. In addition, 4 of 5 women (80%) in the APR group had a living embryo at follow-up.

APR providers are taking legal action to preserve a woman’s access to APR healthcare

Groups that advocate for abortion have sought to block access to APR therapy. They filed lawsuits, passed laws, and threatened medical license revocation to stop clinicians from providing women with APR healthcare., , APR providers are taking legal action to defend access to APR., , These attempts to block access to APR therapy prevent women from exercising their right to choose pregnancy.

Women have the right to know the facts about APR therapy

APR is a time-sensitive therapy. Women who seek to reverse the abortion pill after taking mifepristone must urgently receive progesterone. However, many women are unaware of APR therapy because abortion pill providers withhold this information from them. This lack of information can cause a delay in receiving APR, which can result in embryo death. Clinicians must inform women of APR therapy because they have a right to know all their options before taking the abortion pill.

For additional information

Women should visit AbortionPillReversal.com to learn more about APR therapy. Physicians should visit APRNworldwide.com/join to join the medical network. Those seeking to understand APR medical evidence should visit APRScience.org.

Read, download, and print this document with all the references and citations below:

This browser does not support inline PDFs. Please download the PDF to view it: Download PDF